GM6 Development

Development of GM6, an Innovative First-in-Class Pleiotropic Peptide with Broad CNS Potential

  • GM6 is a 6-amino-acid peptide and an active analog of the endogenous embryonic stage regulator MNTF.

  • GM6 is able to rapidly transit the human blood-brain barrier given its small size and molecular weight.

  • GM6 has been shown to be safe and well-tolerated in a Phase 1 study, multiple Phase 2A studies, and compassionate use.

  • GM6 is non-mutagenic and does not inhibit typical CYP isoforms or interact with tPA.

  • GM6 is manufactured at low cost through solid-phase synthesis under GMP. 

  • GM6 is stable for 120 months at -20°C and 69 months at 5°C.

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